Under intestinal dysbiosis understood development of the state, which continues for some time and can disappear during the corresponding correction, and if left untreated can transform it into a more severe form.The term includes the presence of intestinal dysbiosis excessive colonization of the small intestine and changes in the microbial composition of the colon.Dysbacteriosis considered bacteriological concept.It can be considered as one of the manifestations or complications of the disease, but not an independent nosology.For extreme intestinal dysbiosis accepted appearance in blood bacteria of the gastrointestinal tract, or sepsis.
Dysbacteriosis small intestine
In identifying dysbiosis intestinal mucosa in its marked increase in the number of some microbes and reducing others.
The reasons for the small intestine dysbiosis include:
- entry into the small intestine excessive amounts of microorganisms ahilii and dysfunction of the ileocecal valve;
- presence of favorable conditions to develop p
Under the influence of adverse effects and a variety of factors that weaken the body's defense mechanisms may change the composition of the microflora of the colon.
in the development of dysbiosis colon importance belongs to iatrogenic factors: the use of antibiotics and sulfonamides, steroids, immunosuppressive drugs, the implementation of radiotherapy, surgical intervention.Antibacterial drugs significantly suppressed not only the pathogenic microbial flora, but also stimulates the growth of normal microflora in the colon.As a result, the microbes trapped outside or endogenous species having drug resistance (Proteus, staphylococci, yeasts, Pseudomonas aeruginosa, enterococci), multiply.
Treatment of dysbiosis
Treatment dysbacteriosis should be comprehensive scheme, and include the following measures designed to ensure that:
- suppress excessive bacterial colonization of the small intestine;
- restore the normal microbial flora of the colon;
- improve digestion and absorption;
- restore impaired bowel motility;
- stimulate reactivity.
dysbiosis treatment with antibacterial drugs
The use of antimicrobials in the treatment of dysbiosis, first of all, is necessary in order to be able to suppress the excessive growth of microbial flora in the small intestine.The most widely applied antibiotics belonging to the group tetracyclines, penicillins, quinolones (tarivid, nitroksolin) cephalosporins and metronidazole .
But antibiotics with a broad spectrum of activity, largely disrupted eubioz in the colon.Therefore they should be used only if the diseases that accompany malabsorption and motility intestine, where, as a rule, in the lumen of the small intestine is released pronounced growth of microbial flora. duration of enteral antibiotic is from 7 to 10 days in normal doses.
In diseases that are accompanied by dysbiosis of the colon, it is recommended to treat with drugs that have a symbiotic microbial flora on a minimal effect and inhibit the growth of staphylococci, Proteus, yeasts and other aggressive strains of microbes.These included antiseptics: ersefuril, intetriks, furazolidone, nitroksolin and others.
In identifying severe dysbiosis caused by staphylococcus, you can use antibiotics: Palin, tarivid, metronidazole (Trichopolum) nevigramon, Biseptol-480 . Reception antimicrobials should be carried out for 10-14 days.If the intestinal fluid or feces appear mushrooms, it should apply Nystatin or levorin .
Treatment of bacterial dysbiosis drugs
Appointment bacterial drugs for the treatment of dysbiosis possible without the implementation of antibiotic therapy or after it.They can be used bifidumbakterin, laktobakterin, bifikol, baktisubtil, enterol, Linex and other means.Duration of treatment with these preparations is from 1 to 2 months.
Primary prevention of dysbiosis considered very complex task that is associated with the organization of general preventive problems: nutrition, improve the environment, improve the welfare and numerous other factors external and internal environment.
Under secondary prevention of dysbiosis understood the rational use of antibiotics and other medicines, which can be broken eubioz, timely and optimal treatment of digestive diseases, which are accompanied by violation microbiocenosis.