Human papilloma viruses are regarded as agents responsible for precancerous lesions of the genitals, as well as the occurrence of squamous cell carcinoma in men and women.HPV is divided into 3 forms according to the degree of potential risk of developing cervical cancer.
forms of HPV oncogenic
In danger posed to human viruses HPV, there are three forms of papillomaviruses:
- oncogenic low risk;
- oncogenic high risk.
By non-tumorigenic papillomaviruses are a group 1, 2, 3, 4, 7, 10, 28, 41 types of viruses.They may be caused by the emergence of plantar warts, flat warts, vulgar warts.
Oncogenic papillomaviruses low risk presented 5, 6, 7, 8, 11, 12, 14, 15, 17, 19, 20, 21, 22, 23, 24, 25, 42, 43, 44 types.They may cause the development of anogenital warts, laryngeal papillomatosis, borodavchatogy epidermoplazii.
For high-risk oncogenic papilloma virus types taken 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 types.Because of them, may cause Bowenoid papulleza
cervical intraepithelial neoplasia.Under the influence of various factors oncogenic papillomaviruses high risk of developing malignancy is caused by a process that was triggered by them.In addition, they are proven etiological factors of cervical cancer.
non-oncogenic HPV never called malignancy process provoked them.Approximately 30% of warts disappear within 6 months, more than 50% will disappear on their own within 2 years and about 75% - for 3 years.
Infection vulgar warts is carried out by contact-household, and mostly occurs in childhood and adolescence.Vulgar warts are epidermal-dermal papules, painted in a grayish-brown color and has a characteristic "warty" surface.Mostly, this kind of warts localized on the dorsum of the hands and fingers.In most cases there is self-healing.
flat warts understood nodules, reaching a diameter of 3 mm and having a flat surface.Mostly they occur on the back of the hands and face.Quite often flat warts develop in adolescence.In most cases, this kind of warts can be cured on their own.
emergence of plantar warts occur on the ground, where pressing shoes.Under the plantar warts is meant a thickening of the stratum corneum, the value of which is 5-10 mm.These thickenings have an irregular shape, and if the pressure on them, it is felt soreness.In rare cases, self-healing can occur.As a rule, the need for local, in most cases, surgery when performed scraping.
Oncogenic HPV low risk
If you have certain conditions oncogenic papillomaviruses low risk of malignancy can be triggered by the process that has been caused by them, but it happens quite rarely.
Genital warts related to HPV oncogenic low risk are the entity having testovatoy konsitentsiey.Lobed structure of genital warts, is shaped like a "cauliflower" or "cockscomb" and are located on a narrow basis.In men, genital warts are localized on the prepuce, coronal sulcus of the glans penis, women - in the vestibule, small and large labia, anus.
manifestation borodavchtatoy epidermodysplasia considered multiple polymorphic flat papules, painted in pink, red and has moderate warty surface.
Infection laryngeal papillomatosis takes place, usually at birth, but can not exclude the transfer of the presence of oral-genital contact.The main symptoms of laryngeal papillomatosis is the occurrence of hoarseness and difficulty swallowing.In severe cases, there may be obstruction of the upper airway.
Oncogenic HPV high-risk oncogenic HPV
high risk may be caused by the development Bowenoid papulosis in which appear flat and domed papules and patches having a smooth, velvety surface.In places mucosal lesions color elements orange-red or brownish, grayish-white.If the lesion appeared on the skin, they can have shades of ash-gray to brownish-black.Development Bowenoid papulosis occurs in men who change sexual partners frequently.Usually during benign.In most cases there is self-healing.Occasionally there is a tendency to invasive growth.